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4-(Trifluoromethyl)nicotinic acid
Home4-(Trifluoromethyl)nicotinic acid

4-(Trifluoromethyl)nicotinic acid

CAS No.:158063-66-2

Appearance:White to pale yellow powder or crystalline solid
HS Code:2933399090
Packing:Sealed packaging; package size is subject to the supply agreement.
Specification:Batch-specific specification (COA)
Storage Condition:Store tightly closed in a cool, dry, well-ventilated area away from incompatible materials. Follow the supplier SDS.
Molecular Formula:C7H4F3NO2
Synonyms4-(Trifluoromethyl)pyridine-3-carboxylic acid|4-Trifluoromethylnicotinic acid|Flonicamid free acid|TFNA
  • Batch-specific specification (COA)

Product Overview

Product Overview

4-(Trifluoromethyl)nicotinic acid (CAS 158063-66-2) is a fluorinated pyridine carboxylic acid with the IUPAC name 4-(trifluoromethyl)pyridine-3-carboxylic acid, molecular formula C7H4F3NO2, and molecular weight 191.11. Its combination of a trifluoromethyl group, pyridine nitrogen, and carboxylic acid functionality makes it a useful intermediate and reference material in agrochemical research, fluorinated heterocycle synthesis, and analytical studies. It is also known as flonicamid free acid.

Key Applications

  • Agrochemical Intermediate: Used in research and synthesis involving fluorinated pyridine agrochemicals and related derivatives.
  • Analytical Reference: Applicable to flonicamid-related studies, method development, and impurity or metabolite analysis, depending on grade.
  • Medicinal Chemistry: Trifluoromethyl pyridine carboxylic acid building block for candidate-molecule design.
  • Custom Synthesis: Supports salt formation, amidation, and further functionalization of the pyridine scaffold.

Product Features

  • Clearly identified by CAS 158063-66-2
  • Combines trifluoromethyl, pyridine, and carboxylic acid functionality
  • Suitable for fluorinated heterocycle and agrochemical route development
  • Research, reference-standard, and industrial uses should be confirmed against the batch COA
Product Advantages
  • Combines trifluoromethyl, pyridine nitrogen, and carboxylic acid functionality
  • Suitable for salt formation, amidation, and fluorinated heterocycle derivatization
  • Supports agrochemical route development and analytical research
Reference Standard
CAS Number158063-66-2
Molecular FormulaC7H4F3NO2
Molecular Weight191.11
AppearanceWhite to pale yellow powder or crystalline solid
Melting Point146-148°C
HS Code2933399090
Quality StandardPurity, moisture, and impurity limits are subject to the batch COA
Product Uses
  • Fluorinated pyridine agrochemical intermediate
  • Flonicamid-related analysis and research
  • Building block for medicinal chemistry and custom synthesis
Product Photos
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Chemical Properties

4-(Trifluoromethyl)nicotinic acid
CAS No.
158063-66-2
Appearance
White to pale yellow powder or crystalline solid
HS Code
2933399090
Packing
Sealed packaging; package size is subject to the supply agreement.
Storage Condition
Store tightly closed in a cool, dry, well-ventilated area away from incompatible materials. Follow the supplier SDS.
Matter Classification
Nitrogen heterocyclic carboxylic acid; fluorinated pyridine derivative
Category
Pharmaceutical and Agrochemical Intermediate; Heterocycle
Molecular Formula
C7H4F3NO2
Molecular Weight
191.11
Specification
Batch-specific specification (COA)
IUPAC
4-(trifluoromethyl)pyridine-3-carboxylic acid
PSA
50.2 Ų
InChIKey
LMRJHNFECNKDKH-UHFFFAOYSA-N
SMILES
C1=CN=CC(=C1C(F)(F)F)C(=O)O
Melting Point
146-148°C
Boiling Point
290.4±40.0 °C at 760 mmHg
Density
1.5±0.1 g/cm3
Flash Point
129.4±27.3 °C

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